Post : Senior Lecturer in Tuberculosis and Respiratory Medicine (Pulmonary Medicine)
Department : Vocational Higher Secondary Education
Category Code : 200/2017
Qualification : MD (TB & Respiratory Diseases) / MD (Tuberculosis & Chest Diseases) / DNB (Tuberculosis & Chest Diseases + Permanent Registration under State Medical Council
Date of Test : 15-03-2018
- Alpha 1 anti trypsine deficiency is caused by mutation in the gene
- SERPINA1
- ACVRL1
- SFTPA2
- CSF2RA
- At the end of a deep breath what percent of lung volume is air?
- 60
- 80
- 70
- 90
- Fibre types in respiratory muscles that help in sneezing and coughing is
- Type I
- Type IIa
- Type IIb
- Type IIx
- Most common pattern of ILD in Rheumatoid arthritis is
- UIP
- COP
- NSIP
- DIP
- Fall in FEV1 in non-smoking adults are at the rate of
- 15 ml/year
- 30 ml/year
- 45ml/year
- 60ml/year
- All are true regarding COPD exacerbations, except
- Best predictor of future exacerbations
- More common in patients with chronic cough and sputum production
- Spirometry during the acute exacerbation is usually helpful in predicting the severity and duration
- Many of these eventually resolve without specific treatment
- All are causes of exacerbations of asthma, except
- Rhino virus
- Hemophilus influenza
- Chlamydia
- Para influenza virus
- Anti inflammatory action of theophyllins are mediated through
- Phosphodiesterase
- Histone deacetylase2
- All of these
- None of these
- NSAID well tolerated in Aspirin induced asthma is
- Indomethacine
- Ketorolac
- Piroxicam
- Sodium salicylate
- Prevalence of exercise induced asthma may be more in the following group
- Children
- Elite athletes
- All of these
- None of these
- The most effective drug in exercise induced asthma is
- Beta adrenergic agonists
- Chromolin sodium
- Theophyllins
- Leukotriene antagonists
- Pathognomonic of ABPA among the following is
- Elevated aspergillus specific IgE
- Elevated aspergillus specific IgG
- Charcot-Leyden crystals
- Hyphae filled mucous plug
- Unilateral vocal cord paralysis causes
- Variable intrathoracic obstruction
- Variable extra thoracic obstruction
- Fixed intrathoracic obstruction
- Fixed extra thoracic obstruction
- Most common type of benign tracheal tumour is
- Chondroma
- Papilloma
- Hemangioma
- Hamartoma
- All are true in Vocal Cord Dysfunction, except
- Stridor/wheeze
- Symptoms may remit without treatment
- Presence of bronchial hyper responsiveness
- Normal alveolar arterial gradient
- F508 del mutation in cystic fibrosis results in
- Block in processing
- Block in regulation
- Altered conductance
- Reduced synthesis
- Risk factors for liver disease in cystic fibrosis are all the following, except
- Meconium ileus
- PiZ heterozygous state
- TGF beta-1 polymorphism
- Female sex
- Infections with the following organism is associated with development of bronchiectasis.
- Streptococcus pneumoniae
- Haemophilus influenzae
- Staphylococcus aureus
- Morexella catarrhalis
- Most common form of ILD is
- Hypersensitivity pneumonitis
- Sarcoidosis
- CT-ILD
- IPF
- Differentiating feature between RB-ILD and DIP is
- Age of onset
- Involvement of alveoli
- Smoking score more than 30 pack years
- Golden brown pigments in macrophages
- Detergent workers disease is caused by
- Cladosporium spp.
- Pseudomonas spp.
- Aureobasidium spp.
- Bacillus subtilis
- Shrinking lung syndrome is seen in
- SLE
- Emphysema
- IPF
- Scleroderma
- All are true regarding Rheumatoid pleural effusion, except
- Low sugar
- Leukocytosis
- pH more than 7.2
- Exudative effusion
- Radiologic appearance of PLCH include all, except
- Mid and lower zone involvement
- Ill defined nodules
- Cysts of bizarre shape
- Pleural thickening
- All are true regarding Alveolar microlithiasis, except
- Autosomal recessive disorder
- Calcium metabolism disorder
- Asymptomatic with abnormal CXR
- Mutation in Type II b sodium phosphate cotransporter gene
- In which year Robert Koch received Nobel Prize for his contribution in the field of Tuberculosis?
- 1888
- 1905
- 1912
- 1886
- National Tuberculosis programme was started in India in the year
- 1906
- 1956
- 1978
- 1962
- Swimming pool granuloma is caused by
- M.marinum
- M.ulcerans
- M.avium
- M.smegmatis
- All are solid culture media in Tuberculosis, except
- L-J medium
- Loeffler serum slope
- Middlebrooks medium
- Pawlowskys medium
- Most common form of skeletal tuberculosis is
- Tuberculosis of hip
- Tuberculosis of knee joint
- Spinal tuberculosis
- Tuberculosis of shoulder joint
- Which of the following is unusual in Churg stauss syndrome?
- cANCA
- Elevated ESR
- Elevated CRP
- Elevated Eosinophil Count
- Which is not true in chylothorax?
- Lymphocyte predominant
- Exudate
- Elevated LDH
- Pleural fluid triglyceride more than 110 mg/dl
- Triad of Yellow nail syndrome consists of all, except
- Nail changes
- Pleural effusion
- Bronchiectasis
- Lymphedema
- Most common lung cancer type associated with pleural involvement
- Squamous cell carcinoma
- Adenocarcinoma
- Large cell carcinoma
- Small cell carcinoma
- All are true regarding pleural effusion associated with mesothelioma, except
- Presence of hyaluronic acid is diagnostic
- Low pH
- Low sugar
- LDH concentration greater than that of carcinoma of pleura
- Haller index suggesting significant sternal depression in Pectus excavatum is
- 2.5
- More than 3.25
- Less than 3.25
- Less than 2.5
- Chronic mountain sickness is characterized by all the features, except
- Dyspnoea on exertion
- Extreme polycythemia
- Elevated haematocrit
- Pulmonary hypertension
- EGFR mutations positive lung cancers have all the following features, except
- Exclusively in NSCLC
- More in women
- More in smokers
- 20-30% Asian lung cancer patients
- Carcinoid syndrome is seen in all, except
- Carcinoid tumours
- Large cell carcinoma
- Squamous cell carcinoma
- Small cell carcinoma
- Hypercalcemia most frequently occur in
- Squamous cell cancer
- Adenocarcinoma
- Small cell lung cancer
- Large cell carcinoma
- Spherical pneumonia is associated with
- Streptococcal pneumonia
- Haemophilus influenza
- Coxiella burnetti
- All of these
- Which is not true about pneumatoceles?
- Seen in young children
- Develop late in the course of pneumonia
- Thin walled air filled spaces
- Disappear in a few months
- Liver function abnormalities and clinical hepatitis in atypical pneumonia usually suggest
- Qfever
- Mycoplasma pneumonia
- Legionella pneumonia
- Chlamydia pneumonia
- Lemmiere syndrome is caused by
- M.abscesus
- Peptostreptococcus
- Prevotella oralis
- F.necrophorum
- Important infection in post transplant patients, beyond one month post surgery is
- CMV
- P. jiroveci
- A. fumigates
- Nocardia asteroides
- Mechanism of action of fluoroquinolones is
- Inhibition of protein synthesis
- Interfere with DNA gyrase/topoisomerase IV leading to cell wall lysis
- LPS mediated increased cell wall permeability to antibiotics
- Both 'Inhibition of protein synthesis' and 'Interfere with DNA gyrase/topoisomerase IV leading to cell wall lysis'
- Most common site for aspiration pneumonia is
- Superior segment of RLL
- Posterior segment of LUL
- Medial segment of RML
- Superior segment of LLL
- Most likely diagnosis in an edentulous patient presenting with a cavitating lesion in CXR in all, except
- Bronchial obstruction
- Pulmonary embolus
- Septic embolus
- Lung abscess
- Diagnostic threshold for BAL in nosocomial pneumonia is
- 105/ CFU/ml
- 103 CFU/ml
- 104 CFU/ml
- 106 CFU/ml
- Which of the following mycobacteriae is not associated with human infection?
- M.africanum
- M.canettii
- M.bovis BCG
- M.caprae
- Droplet nuclei are not the mode of transmission among the following diseases
- Measles
- Tuberculosis
- Influenza
- Varicella
- Most common form of extrapulmonary tuberculosis is
- Pleural effusion
- Spinal tuberculosis
- Genitourinary TB
- Lymphnode TB
- All are true about Xpert-MTB-RIF, except
- Nucleic acid amplification test
- Sophisticated laboratory needed, not useful in resource poor settings
- Simultaneously detects RIF resistance
- Specificity 90-100%
- Diagnostic test of choice in pneumocystis jerovecii, is
- Diff-Quick stain
- Induced sputum with direct immunofluorescent staining
- Wright's stain
- Toluidine blue O
- Mechanism of Bleomycin lung toxicity include all, except
- Generation of oxygen free radicals
- Direct effects on DNA
- Absence of enzyme Bleomycin hydrolase
- Inhibition of enzyme Bleomycin hydrolase
- Which is not correct about omalizumab?
- Recombinant humanised antibody
- Dose dependent on serum level of IgE alone
- Indicated in moderate to severe allergic asthma
- Should not be initiated at acute stage of asthma
- IRIS can occur in all the following conditions in a patient with HIV, except
- Mycobacterium tuberculosis
- Leishmaniasis
- Fungal infections
- Bacterial pneumonia
- Permissive hyper capnoea is used in all the following, except
- Acute lung injury
- Increased intracerebral pressure
- ARDS
- Neonatal respiratory failure
- Oral bio-availability is maximum for which among the following inhaled steroids?
- Fluticasone
- Mometasone
- Ciclasonide
- Beclomethasone
- All are features of chronic eosinophilic pneumonia, except
- Elevated eosinophil count in blood and BAL
- Reverse pulmonary edema pattern in CXR
- Male sex predominance
- Presence of interstitial fibrosis pathologic hall mark
- Chronic pleuritic pain is characteristic in
- Lung cancer
- Pneumoconiosis
- Pulmonary embolism
- Mesothelioma
- Absolute contraindication for argonplasma coagulation is
- Implantable defibrillator
- FiO2 less than 0.4
- Major airway bleed
- Post infectious airway stenosis
- Elevated DLCo in asthma is due to
- Associated large lung volume
- Increased perfusion of well ventilated upper zones
- None of these
- both 'Associated large lung volume' & 'Increased perfusion of well ventilated upper zones'
- Varenicline helps in smoking cessation by i) Being partial agonist of nicotinic cholinergic receptor ii) Blocks effects of smoke on nicotine receptor iii) As a result of receptor blockade nicotine withdrawal symptoms are relieved iv) Desire to smoke is reduced
- i, ii and iii
- ii, iii and iv
- i, ii and iv
- i, iii and iv
- Which is not true about Pancoast syndrome?
- Most common initial symptom is shoulder pain
- Intrinsic muscles of the hand may be involved
- Associated with superior sulcus tumour
- CT is superior imaging modality
- Malignancy commonly associated with airway metastasis is
- Prostatic cancer
- Colon cancer
- Osteogenic sarcoma
- Ca. Tongue
- Criteria for diagnosing a definite Hereditary Hemorrhagic Telangiectasia include all, except
- Recurrent spontaneous nose bleeds
- Mucocutaneous telangiectasia
- No first degree relative involved
- Visceral involvement
- Skin manifestation that is specific for sarcoidosis
- Erythema nodosum
- Lupus pernio
- Subcutaneous nodules
- Plaques
- Not true about Idiopathic Pulmonary Hemosiderosis, from the following is
- Predominantly disease of children
- Recurrent haemoptysis
- Renal involvement is common
- Histology of lung shows bland alveolar haemorrhage with hemosiderin accumulation
- The commonest type of lung carcinoma seen in women and non-smokers
- Adenocarcinoma
- Large cell carcinoma
- Small cell carcinoma
- Squamous cell carcinoma
- The commonest malignant tumour seen in asbestos worker
- Bronchogenic carcinoma
- Gastric carcinoma
- Glioblastoma multiforme
- Malignant mesothelioma
- Cushing syndrome is usually associated with all, except
- Carcinoid tumour
- Squamous cell carcinoma
- Neuroblastoma
- Small cell carcinoma
- Most common radiological pattern associated with Bronchioloalveolar carcinoma
- Multiple nodular lesions
- Consolidative pattern
- Perihilar opacity with cavitation
- Single nodular lesions
- The commonest type of emphysema
- Irregular
- Centriacinar
- Panacinar
- Paraseptal
- The pneumoconiosis which can be seen commonly in tobacco smokers is
- Anthrocosis
- Byssinosis
- Siderosis
- Silicosis
- The type of pneumoconiosis in which eggshell calcification of hilar lymph nodes is seen in chest X-ray is
- Anthracosis
- Berylliosis
- Coalworkers pneumoconiosis
- Silicosis
- Bronchial carcinoma can be associated with all except
- Acanthosis nigricans
- Myesthenia gravis
- Hypercalcaemia
- SIADH
- All are true about asbestosis except
- Asteriod bodies are characteristic
- Begins in the lower lobe and subpleurally
- Marked diffuse pulmonary interstial fibrosis
- Pleural plaques most common manifestation
- All are true about silicosis except
- Most prevalent chronic occupational disease in the world
- Quartz is most commonly implicated form
- Initial lesions tend to localize in the lower lung zone
- There is no known clear association of silica and development of lung cancer
- Bedaquiline is not started in MDR TB in all the situations, except
- Pyrazinamide and at least 4 second line drugs are not available according to sensitivity tests
- Uncontrolled cardiac arrhythmia requiring medication
- Prolonged QT interval (more than 450 ms)
- Presence of chorioretinitis
- Which of the following river is known as 'Sorrow of Bengal'?
- Ganga
- Damodar
- Brahmaputra
- Yamuna
- The best indicator of economic development of any country is
- Per capita income
- Agriculture
- Transport
- Gross production
- Sumita Sanyal was associated with which field?
- Politics
- Sports
- Science
- Film Industry
- The headquarters of UNESCO
- Paris
- New York
- Rome
- Geneva
- Year of Poona Pact
- 1919
- 1929
- 1932
- 1942
- Founder of Sadhujana Paripalana Sangham
- Sree Narayana Guru
- Pandit Karuppan
- Ayyankali
- Thycaud Ayya
- What is the full form of NCERT?
- National Council for Educational Resources and Teaching
- National Council of Employees Remedial Teaching
- National Council of Educational Research and Training
- National Council for Employees Research and Training
- The 18th anniversary of Kargil Vijay Diwas has celebrated on which day in India?
- 2017 July 22
- 2017 June 22
- 2017 July 26
- 2017 June 26
- Who issued the famous 'Kundara Proclamation'?
- Pazhassi Raja
- Velu Thampi Dalawa
- Marthanda Varma
- Paliathachan
- 'Jathikummi' was the famous work of
- Dr. Palpu
- V. T. Bhattathirippad
- Kumaranasan
- Pandit Karuppan
- Atma Vidya Sangham was founded by
- Vagbhatananda
- Sahodaran Ayyappan
- Velukkutty Arayan
- Brahmananda Swami Sivayogi
- Temple Entry Proclamation was issued by
- Marthanda Varma
- Swathithirunnal
- Darmaraja
- Sree Chithira Thirunal Balarama Varma
- In the National Flag which colour is used in the wheel?
- Red
- Navy Blue
- green
- White
- First Five Year Plan was started in which year?
- 1949
- 1951
- 1959
- 1961
- First Regular Indian Censes was conducted in
- 1889
- 1888
- 1881
- 1880
- 2017 World Athletic Championship was held at
- New York
- Russia
- Germany
- London
- Founder of Travancore Muslim Mahajana Sabha
- Vakkom Adbul Khadar Moulavi
- Khan Abdul Gafferkhan
- Sayyed Ahamed Khan
- Muhammed Abdu Rahman Saheb
- Who was honoured with the title 'Bharata Kesari' by the President of India?
- Sree Narayana Guru
- Mannathu Padmanabha Pillai
- Kumara Guru
- Kumaranasan
- The famous tourist centre Ajanta is situated at
- Gujarat
- Goa
- Madhya Pradesh
- Maharashtra
- 1857 Revolt was started at
- Meerut
- Jhansi
- Kanpur
- Bihar
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