Post: Assistant Professor in Infectious Diseases
Department: Medical Education Service
Category Code: 72/17
Qualification: DNB; MBBS
Question Paper Code: 59/18
Date of Test: 10-05-2018
- Paradoxical carrier is defined as
- A carrier who has never suffered from the disease caused by the pathogen.
- A carrier status for more than 6 months duration.
- A carrier who acquires the pathogen from another carrier.
- None of these
- Causative organism for valley fever is
- Blastomyces dermatitidis
- Histoplasma capsulatum
- Paracoccidiodes brasiliensis
- Coccidiodes Immitis
- Drug of choice for invasive Aspergillosis
- Voriconazole
- Amphotericin deoxycholate
- Micafungin
- Liposomal Amphotericin
- As per Biomedical waste segregation [BMW] 2016 rules, contaminated recyclable waste should be disposed in
- Blue cardboard with blue label
- Yellow bags
- White punctures proof containers
- Red bags
- Most common organism responsible for sepsis following dog bite is
- Streptobacillus moniliformis
- Pasteurella Multocida
- Capnocytophaga canimorsus
- Bartonella bacilliformis
- Tropical fever syndrome usually associated with sensory neural deafness is
- Scrub typhus
- Chikungunya
- Dengue Haemorrhagic fever
- Leptospirosis
- Urinary antigen test may be useful in the diagnosis of all the following except.
- Histoplasmosis
- Pontiac fever
- Pneumococcal pneumonia
- Brucellosis
- Drug of choice for Methicillin Susceptible Staphylococcus Aureus [MSSA] bacteremia is
- Cloxacillin
- Vancomycin
- Daptomycin
- Linezoli d
- Mutation detected by CB-NAAT[GenXpert] is
- katG
- rpoB
- inhA
- All of these
- Name the organism susceptible to intravenous Polymyxin E.
- Staphylococcus Aureus.
- Bacteriodes fragilis.
- Pseudomonas Aeuroginosa.
- Serratia Marcescens.
- Avian Influenza outbreak in Kuttanad in 2016 was due to
- H1N1
- H3N2
- H5N1
- H7N2
- MERS is caused by
- Metapneumo virus
- Orthomyxo virus
- Paramyxo virus
- Corona virus
- Antibiotics exhibiting concentration dependend bactericidal activity include all the following except
- Cefuroxime
- Ciprofloxacin
- Amikacin
- Metronidazole
- Delhi declaration for AMR[Antimicrobial Resistance] containment was in the year
- 2011
- 2017
- 2015
- 2013
- High level INH resistance in Mycobacterium tuberculosis is due to the presence of mutations in which gene?
- catG
- inhA
- rpoB
- rrs
- Corynebacterium species implicated in prosthetic valve endocarditis.
- Corynebacterium ulcerans
- Corynebacterium jeikeium
- Corynebacterium hofmanni
- Corynebacterium xerosis
- All of the following are features of postpartum clostridium sordelli toxic shock syndrome except
- Haemoconcentration
- Lack of purulent discharge
- High grade fever
- Peripheral edema and effusion
- Route of administration of Zanamivir for H1N1 influenza is
- Intravenous
- Oral
- Inhalation
- Intramuscular
- Viral haemorrhagic fever with case fatality rate of 40 to 50% is
- Hantavirus pulmonary syndrome
- Kyasanur forest disease
- Dengue Hemorrhagic fever
- Yellow fever
- Common etiologic agents of infection in splenectomized patients are all except
- Pseudomonas Aeruginosa
- Streptococcus pneumoniae
- Salmonella
- Haemophilus influenza
- All the following statements about meningococcemia are true except
- Most often affects young children.
- Rapidly progressive form is usually associated with meningitis.
- Almost three-quarters of patients will have a rash.
- Household members of index case are at 400-800 times greater risk of contacting disease than the general population.
- Septic shock and bullous hemorrhagic skin lesions after ingestion of contaminated shell fish is associated with
- Aeromonas hydrophila
- Pseudomonas Aeruginosa
- Capnocytophaga canimorsus
- Vibrio vulnificus
- All the following are features of cerebral malaria except
- Photophobia is rare.
- Symmetric encephalopathy is typical.
- Nuchal rigidity is common.
- Unrecognized infection results in 20 to 30% mortality rate.
- All the following statements about infective endocarditis are true except
- Injection drug users usually develop tricuspid valve endocarditis.
- Microabscess in brain and meninges occur commonly in streptoccal endocarditis.
- Endocarditis caused by nutritional variant streptococci is treated with regimen for moderately penicillin resistant streptococci.
- Sensitivity of Transthoracic echocardiography to detect vegetations is 65%.
- Bacterial food poisoning with shortest incubation period is due to
- Vibrio cholera.
- Salmonella typhimurium.
- Staphylococcus aureus.
- Clostridium Perfringens.
- Antibiotic that pose significantly less risk for development of clostridium difficile colitis is
- Ciprofloxacin
- Cefuroxime
- Clindamycin
- Penicillin
- Painless, non-tender, indurated ulcers with firm, non-tender inguinal adenopathy is suggestive of
- Chancroid
- Lymphogranuloma venereum
- Primary syphilis
- Ureaplasma urealyticum
- Which of the following drugs does not require dose adjustment in renal insufficiency?
- Tenofovir alafenamide
- Zidovudine
- Tenofovir disoproxil fumarate
- Abacavir
- Early onset health-care associated pneumonia is usually due to
- Klebsiella pneumoniae
- MRSA
- Streptococcus pneumoniae
- Acinetobacter baumanni
- All the following are components of ventilator associated pneumonia bundle except
- Elevation of head end of bed to 60°.
- Daily sedation interruption.
- Peptic ulcer disease prophylaxis.
- Deep vein thrombosis prophylaxis.
- Infections occurring in recipient within one month of hematopoietic stem cell transplant include all the following except.
- Candida
- CMV
- HSV
- HHV-6
- All the following organisms are susceptible to cotrimoxazole except.
- Nocardia
- Cryptosporidium parvum
- Isospora belli
- Stenotrophomonas maltophila
- All the following drugs can be used in the treatment of CMV pneumonia except.
- Valacyclovir
- Foscarnet
- Cidofovir
- Ganciclovir
- Name the antibiotic that acts by disrupting membrane permeability by electrostatic charge alteration.
- Tigecycline
- Fosfomycin
- Nitrofurantoin
- Polymyxin B
- Serotonin syndrome when coadministered with selective serotonin reuptake inhibitors is observed with.
- Clarithromycin
- Aztreonam
- Linezolid
- Cefepime
- Concurrence of pneumococcal pneumonia,endocarditis and meningitis is referred to as
- Austrian's triad
- Beck's triad
- Dieulafoy's triad
- Anderson triad
- All the following are TRUE about diphtheria EXCEPT.
- Pseudomembrane in diphtheria is tightly adherent to underlying tissues.
- High grade fever.
- Diphtheria antitoxin cannot neutralize cell bound toxin.
- Diphtheria neuropathy is a non-inflammatory demyelinating disorder mediated by exotoxin.
- The process by which Plasmodium falciparum infected RBCs adher to uninfected RBCs is referred to as
- Rosette
- Cytoadherence
- Agglutination
- Emperipolesis
- Which of the following is not usually seen in children with severe malaria?
- Deep jaundice
- Metabolic acidosis
- Hypoglycemia
- Severe Anaemia
- Organism implicated in granulomatosis infantiseptica is
- Bartonella henselae
- Brucella abortus
- Coxiella Burnetti
- Listeria monocytogenes
- All the following statements are TRUE about tetanus EXCEPT
- Median time after onset of injury is seven days.
- Neonatal tetanus is usually generalized.
- Cerebrospinal fluid examination shows lymphocytic pleocytosis.
- Ablett classification is used to asses clinical severity of tetanus.
- All the followings drugs can be used in treatment of mucormycosis except
- Amphotericin deoxycholate
- Posaconazole
- Ravuconazole
- Micafungin
- Modified Hodge test is used to detect resistance to
- Macrolides
- Aminoglycosides
- Quinolones
- Carbapenems
- Heterophile negative mononucleosis is seen in all EXCEPT
- Toxoplasmosis.
- HIV
- CMV
- EBV
- All the following statements are TRUE about food-borne botulism EXCEPT
- Paralytic ileus is common.
- Symmetric ascending paralysis is characteristic
- Fever is usually absent.
- Incubation period depends on toxin dose.
- Spontaneous non-traumatic myonecrosis in patients with carcinoma of gastrointestinal tract is usually due to
- Clostridium perfringens
- Clostridium septicum
- Streptococcus bovis
- Clostridium ramosum
- All the following drugs can be used for chemoprophylaxis against meningococcal disease EXCEPT.
- Rifampin.
- Ciprofloxacin.
- Azithromycin.
- Cotrimoxazole.
- All the following statements are TRUE about Gonococcal infections EXCEPT
- Acute urethritis is the most common manifestation of gonorrhea in males.
- Axial skeleton is usually involved in gonococcal arthritis.
- Clinical manifestations of gonococcal urethritis are more severe than those of non-gonococcal urethritis.
- Menstruation is a risk factor for gonococcal arthritis.
- Presence of gram negative coccobacilli in CSF is suggestive of meningitis due to
- Pneumococci
- Haemophilus Influenzae
- Meningococci
- Listeria monocytogenes
- All the following statements about nocardiosis are TRUE EXCEPT.
- Nocardia Asteroides complex is the most commonly isolated nocardia species from clinical specimens.
- Risk of disseminated disease is higher in patients with deficient humoral immunity.
- Nocardia farcinica is more virulent and prone to dissemination.
- Sulfonamides are the drugs of choice for Nocardiosis.
- All the following statements are TRUE about actinomycosis EXCEPT
- Pelvic Actinomycosis is commonly associated with IUCD use.
- Mediastinal infection is uncommon.
- Actinomyces israelii is not an acid-fast organism.
- Sulfur granules are pathognomonic of actinomycosis.
- All the following statements are TRUE about military tuberculosis EXCEPT
- Cryptic Miliary Tuberculosis is seen in infants.
- Non-reactive military tuberculosis is an acute septicemic form.
- Choroid tubercles are seen in upto 30% of cases.
- Sputum smear microscopy is negative in up to 80% of cases.
- Lucio's phenomenon is seen in
- Treated lepromatous leprosy.
- Untreated lepromatous leprosy.
- Treated tuberculoid leprosy.
- Untreated tuberculoid leprosy.
- All the following Non-tuberculous mycobacteria are rapid growers except.
- M.chelonae
- M.Abscessus
- M.Fortuitum
- M.Kansasii
- Which antimycobacterial agent requires dose modification when creatinine clearance is < 30 ml/min.
- Isoniazid
- Rifampicin
- Rifabutin
- Pyrazinamide
- All the following statements are TRUE about neurosyphilis EXCEPT
- CSF VDRL has high specificity but low sensitivity.
- CSF VDRL sensitivity is highest in tabes dorsalis.
- A non-reactive CSF FTA test may be used to rule out neurosyphilis.
- Meningovascular syphilis presents as a gradually progressive vascular syndrome.
- All the following statements are true about Weil's syndrome except.
- Mortality rates are 5 to 15%.
- Associated with severe hepatic necrosis.
- Splenomegaly is seen in 20% of cases.
- Elevated creatinine kinase helps to differentiate it from viral hepatitis.
- Drug of choice for treating scrub typhus in pregnancy is
- Ceftriaxone
- Doxycycline
- Azithromycin
- Clarithromycin
- Which of the following is the commonest clinical finding in enteric fever?
- Coated tongue
- Rose spots
- Abdominal tenderness
- Hepatosplenomegaly
- Pastia's lines are characteristically seen in
- Staphylococcal toxic shock syndrome.
- Scarlet fever.
- IMN.
- Kawasaki disease.
- Serum Galactomannan may help in the diagnosis of
- Mucormycosis.
- Invasive aspergillosis.
- Cryptococcosis.
- Candidemia
- Bullous myringitis in a patient with pneumonia is suggestive of infection due to
- Coxiella Burnetti
- Legionella Pneumophila
- Haemophilus influenzae
- Mycoplasma Pneumoniae
- All the following drugs can be used to treat MRSA bacteremia EXCEPT
- Linezolid
- Teicoplanin
- Daptomycin
- Vancomycin
- All the following are caused by Flavi viruses EXCEPT
- Hepatitis C
- West Nile
- Ebola
- Yellow fever
- All the following statements are TRUE about oseltamivir EXCEPT
- Excreted primarily by the kidneys.
- Neuropsychiatric side effects are more common in children.
- Not effective against Influenza B.
- Resistance develop by changes in viral Neuraminidase enzyme.
- Antimicrobial spectrum of Tigecycline includes all the following EXCEPT
- Klebsiella pneumoniae
- Acinetobacter baumanni
- MRSA
- Pseudomonas Aeruginosa
- Nitrofurantoin is indicated in the treatment of E.coli.
- Cystitis
- Pyelonephritis
- Bacteremia
- Osteomyelitis
- CENTOR scoring system [criteria] is used to diagnose
- IMN
- Diphtheria
- Streptococcal Pharyngitis
- Pertussis
- Asymptomatic bacteriuria should be treated in all the following situations EXCEPT
- Catheterised patients.
- Post renal transplant.
- Prior to urological intervention.
- Pregnancy
- Duncan's disease is associated with
- EBV
- HHV-6
- HHV-8
- CMV
- Parvovirus infection is associated with all the following EXCEPT
- Milker's nodules
- Hydrops fetalis
- Chronic Anaemia
- Polyarthropathy syndrome
- All the following statements are true about Human Papilloma Virus [HPV] infection EXCEPT
- Quadrivalent HPV Vaccine is licensed for administration in girls and young women between 9 to 26 years of age.
- HPV types 6 and 11 cause 90% of anogenital warts.
- Cervical cancer screening is not required in quadrivalent HPV vaccinated ladies.
- Epidermodysplasia verruciformis is associated with HPV infection.
- All the following statements are true about HIVAN[HIV associated nephropathy] EXCEPT
- Proteinuria is the hallmark of HIVAN.
- USG reveals bilaterally symmetrical contracted kidneys.
- FSGS is present in 80%.
- Edema and hypertension are rare.
- Vacuolar myelopathy in HIV is similar to
- Conus cauda syndrome.
- Subacute combined degeneration of the cord
- Ataxic hemiparesis.
- Freidrich's ataxia
- All the following statements are TRUE EXCEPT
- Herpangina is caused by coxsackievirus A.
- Hand -foot-and-mouth disease is caused by coxsackievirus A-16 or enterovirus 71.
- Erythematous halo differentiate koplik's spots from Fordyce's spots.
- Hecht's pneumonia is usually seen in immunocompetent healthy adults.
- All the following statements are TRUE about mumps EXCEPT
- Mumps meningitis can occur in the absence of parotitis.
- Sterility after mumps orchitis is rare.
- Hypoglycorrhachia is seen in mumps meningitis.
- Glucocorticoids and tunica albuginea incision are recommended in severe mumps orchitis.
- Babes nodules are seen in
- Cerebral malaria
- Neurobrucellosis
- Rabies
- Lyme's disease
- Primary Amoebic meningoencephalitis is caused by
- Balmuthia mandrillaris
- Acanthamoeba cultbersoni
- Naegleria fowled
- Angiostrongylus cantonensis
- Human monoclonal antibody Bezlotoxumab is used in the treatment of
- Babesiosis
- HIV
- Clostridium difficile colitis
- Ebola
- Using the right drug at the right dose at the right time for the right duration for the right patient, inorder to minimize collateral damage due to alteration of gut microbiota is referred to as
- Antibiotic heterogeneity
- Antibiotic optimization
- Antibiotic apocalypse
- Antibiotic stewardship
- Name of the boat which caused the demise of Sri Kumaranasan
- INS Vikrant
- INS Garuda
- Redeemer
- INS Kalpa
- The famous text ‘Siddhanubhooti’ is written by
- Chattampi Swamikal
- Brahmananda Sivayogi
- Swami Vivekananda
- Ramakrishna Paramahansa
- The first moon exploration mission of India
- Mangalyan
- Agni-I
- Chandrayan-I
- Agni-II
- Muslim scholar, journalist, freedom fighter and the newspaper proprietor of Travancore
- Vakkom Maulavi
- Moulana Azad
- Moulana Shoukath Ali
- Muhammed Ali Jinnah
- ‘Mitavadi’ was published from Talassery in
- 1905
- 1906
- 1907
- 1910
- Real name of Thaycaud Ayya is
- Subharaya
- Sukumaran
- Subbarao
- Subharao
- World Yoga day is on
- 21st March
- 21st April
- 21st May
- 21st June
- Right to information Act is not applicable to
- Punjab
- Rajasthan
- Jammu Kashmir
- Goa
- Who is renowned as First Generation Feminist?
- Sara Joseph
- Sarojini Naidu
- Vijaya Lakshmi Pandit
- Anna Chandi
- Mathrubhoomi became a daily from
- 1930 April
- 1931 April
- 1913 April
- 1929 April
- ‘Pratyaksha Raksha Daivasabha’ founded by
- Sahodaran Ayyappan
- Ayyankali
- K. Kelappan
- Poykayil Yohannan
- Auto Biography of G. Sankara Kuruppu
- Olavum theeravum
- Ormayude Olangalil
- Oru desathinte Katha
- Ente Katha
- ‘Shrimati’, a magazine founded and edited by
- Akkamma Cheriyan
- Anna Chandy
- Kuttimalu Amma
- Arya Pallam
- The education commission deputed for secondary education
- Radhakrishna Commission
- Kothari Commission
- Hunter Commission
- Muthaliar Commission
- The social reformer who is known as ‘Lincoln of Kerala’
- Ayyankali
- Pandit Karuppan
- VT Bhattatrippad
- Dr. Palpu
- ‘Atmavidyasangham’ founded by
- Raja Ram Mohan Roy
- Dayananda
- Vagbhadananda
- Vivekananda
- The Article of Constitution which provides the right to Central and State govt. to impose and collect GST.
- Article 246A
- Article 245A
- Article 346A
- Article 345A
- Expansion of AFSPA.
- Armed Forces Special Powers Act
- Armed Forces Special Privileges Act
- Air Forces Special Protection Act
- Armed Forces Super Powers Act
- Urjit Patel, our Reserve Bank Governor belongs to
- Gujarat
- Maharashtra
- Madhya Pradesh
- Uttaranchal
- 69th Amendment of Indian Constitution gives
- Voting age reduced from 21 to 18
- Power of National capital territory to Delhi
- Special power to Jammu Kashmir
- Right to education
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