Pharmacist Grade II Health Service 521/2017 Answer Key

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Post: Pharmacist Grade II
Department: Health Service
Category Code: 521/17
Qualification: Pre­Degree / Plus Two/VHSE + Diploma in Pharmacy (D.Pharm)
Date of Test: 01-06-2018




  1. Drug of choice for the management of status epilepticus
    • Ethosuximide
    • 50% glucose
    • Diazepam
    • Sodium valproate

  2. Pharmacy bill introduced by government of India in the year
    • 1948
    • 2016
    • 1940
    • 1945

  3. Which of the following is a nutritional deficiency disorder?
    • Mumps
    • Marasmus
    • Mycoses
    • Myelitis

  4. The immunoglobulin present in very low concentration in normal serum
    • Ig E
    • Ig M
    • Ig G
    • Ig A

  5. Condition in which WBC is significantly lower than the reference range
    • Pancytopenia
    • Leucocytosis
    • Leucopenia
    • Neutropenia

  6. The science deals with the interaction of exogenously administered chemical molecules with living system
    • Anthropology
    • Bioinformatics
    • Cheminformatics
    • Pharmacology

  7. According to Indian Pharmacopoeia the statement of sparingly soluble at 20° to 30° means approximate volume of solvent in ml per gm of solute is
    • From 1 to 10
    • From 30 to 100
    • From 10 to 30
    • From 100 to 1000

  8. Chief constituent of Bael fruit is
    • Marmelosin
    • Marmesin
    • Mannitol
    • Mannoglycan

  9. Dopamine agonist used in the treatment of Parkinsonism
    • Selegiline
    • Entacapone
    • Bromocriptine
    • Amantadine

  10. Viscous liquid preparations used orally for the relief of cough
    • Gargles
    • Drops
    • Elixirs
    • Linctuses

  11. Schedule Y of D&C Act, 1945 deals with
    • Generic drugs
    • Prescription drugs
    • Clinical trial
    • Medical devices

  12. Permanent contraceptive method
    • Intrauterine devices
    • Depot formulations
    • Non-scalpel vasectomy
    • Menstrual induction

  13. An ultra filtrate of plasma formed by the choroid plexus is
    • Cerebrospinal fluid
    • Amniotic fluid
    • Interstitial fluid
    • Serum

  14. Irritant drugs are not given by
    • Intramuscularly
    • Topically
    • Subcutaneously
    • Intravenously

  15. Along with benzoic acid Whitfield's ointment contains
    • 6% salicylic acid
    • 2% salicylic acid
    • 4% salicylic acid
    • 3% salicylic acid

  16. Which among the following is stored in light resistant container?
    • Albendazole
    • Allopurinol
    • Adrenaline
    • Alprazolam

  17. Which of the following is not an adverse effect of propranolol?
    • Lactic acidosis
    • Depression
    • Bronchospasm
    • Hypotension

  18. Water soluble portion of tragacanth
    • Bassorin
    • Tragacanthin
    • Alginate
    • Agaropectin

  19. Which among the followings do not have an active metabolite?
    • Morphine
    • Neostigmine
    • Diazepam
    • Digitoxin

  20. In filtration anesthesia to prolong the duration of action procaine is mixed with
    • Glycine
    • Procainamide
    • Cocaine
    • Adrenaline

  21. According to NDPS Act, 1985 cultivating coca plant or gathering any portion of coca plant is termed as
    • Production
    • Illicit traffic
    • Preparation
    • Manufacture

  22. Macrocytic anemia developed due to the deficiency of intrinsic factor is known as
    • Pernicious anemia
    • Magaloblastic anemia
    • Hypochromic anemia
    • Sideroblastic anemia

  23. Which of the following is used to ligate large blood vessels?
    • Aneurism clip
    • Foley's catheter
    • Splint
    • Umbilical tape

  24. Theophylline is a non-competitive inhibitor of
    • Phosphodiesterase
    • Peroxidase
    • Aldehyde dehydrogenase
    • Carbonic anhydrase

  25. Intracellular enzyme which is a combination of heme and protein and act as catalyst in biological oxidation are termed as
    • Hemoglobin
    • Cytochromes
    • Creatine kinase
    • Transferrin

  26. Aminophylline is a stable mixture of theophylline with which of the following?
    • Aminocaproic acid
    • Amiloride
    • Ethyl oleate
    • Ethylene diamine

  27. The pharmacokinetic parameter that describes the efficiency of elimination of drug from the body is
    • Half life
    • Clearance
    • Excretion
    • Metabolism

  28. Drug containing saponin glycoside as major constituent
    • Cascara
    • Ginko
    • Brahmi
    • Quassia

  29. Which of the following is an additive drug combination?
    • Amlodipine + Atenolol
    • Histamine + Adrenaline
    • Sulphamethoxazole + Trimethoprime
    • Tyramine + MAO inhibitors

  30. 5-HT antagonist used to control chemotherapy induced nausea and vomiting
    • Risperidone
    • Ondansetrone
    • Cyproheptadine
    • Clozapine

  31. Cardioselective beta blocker
    • Propranolol
    • Timolol
    • Carvedilol
    • Metoprolol

  32. Synthetic Cannabinoid
    • Methadone
    • Tramadol
    • Naloxone
    • Nabilone

  33. Most abundant cation in the extra cellular fluid
    • Potassium
    • Calcium
    • Sodium
    • Chloride

  34. The Medicinal and Toilet Preparations Act came in to force in
    • 1957
    • 1967
    • 1958
    • 1968

  35. Class I B antiarrhythmic drug
    • Disopyramide
    • Amiodarone
    • Lidocaine
    • Verapamil

  36. Causative organism of Plague
    • Arbovirus
    • Rat flea
    • Clostridium tetani
    • Yersinia pestis

  37. All enzymes involved in glycolysis are present in
    • Mitochondria
    • Blood
    • Cytosol
    • Cellwall

  38. The normal range of serum potassium level
    • 96-106 mEq/L
    • 1.5-2.2 mEq/L
    • 136-145 mEq/L
    • 3.5-5.0 mEq/L

  39. Water purified by distillation or reverse osmosis and meets the specifications for purity as per IP which is free from pyrogens and not intended to be sterile is
    • Purified water
    • Sterile water for injection
    • Deionized water
    • Water for injection

  40. The desirable level of total serum cholesterol in adults
    • Less than 200 mg/dL
    • Less than 240 mg/dL
    • More than 200 mg/dL
    • More than 240 mg/dL

  41. Which of the following is mainly used as a diuretic?
    • Ginseng
    • Mustard
    • Ginko
    • Gokhru

  42. Tissue amine widely distributed in plants animals and in the venom of bees and wasps
    • Serotonine
    • Tyramine
    • Histamine
    • Adrenaline

  43. An indication of renal function which is used to estimate glomerular filtration rate is
    • Serum urea
    • Serum alkaline phosphatase
    • Blood urea nitrogen
    • Serum creatinine

  44. Inadequate blood flow to a part of the body secondary to constriction or blockage of the supplying artery
    • Infarction
    • Ischemia
    • Necrosis
    • Eclampsia

  45. Which among the following is an analytical agency constituted for efficient administraiton of D&C Act
    • Central Drugs Laboratory
    • Controlling Authority
    • DTAB
    • Drugs Consultative Committee

  46. A toxoid vaccine is
    • Detoxicated endotoxin
    • Detoxicated cellular fraction
    • Detoxicated exotoxin
    • Antitoxin

  47. The difference that exists between the intake and output of nitrogen both being expressed in terms of grams N per day is
    • Blood Urea Nitrogen
    • Non-Nitrogen Protein
    • Protein Nitrogen
    • Nitrogen balance

  48. Which of the following is a book of secondary entry?
    • Cash book
    • Two column cash book
    • Ledger
    • Journal

  49. The ability of sulphides in highly alkaline pH to reduce the disulphide linkage in the aminoacid cysteine is the principle behind
    • Sulphur candles
    • Sulphite preservatives
    • Sulphide depilatories
    • Sulphate antidotes

  50. Which of the following is deficient in Vitamin D?
    • Cod liver oil
    • Halibut oil
    • Eggs
    • Shark liver oil

  51. Which of the following monoclonal antibody is fully human origin?
    • Daclizumab
    • Infliximab
    • Adalimumab
    • Edrecolomab

  52. The assets and liabilities of a business organization is
    • Profit and loss account
    • Balance Sheet
    • Trial balance
    • Debentures

  53. Centrally acting cough suppressant
    • Ambroxolol
    • Codeine
    • Bromhexine
    • Ammonium bicarbonate

  54. Which of the following is preferred for dressing wounds infected with pyogenic bacteria?
    • Magsulf
    • Eusol
    • AF lotion
    • Mercurochrome solution

  55. The quantity of sodium chloride required to prepare 400 ml of 0.9% solution
    • 2.6 gm
    • 3.25 gm
    • 3.6 gm
    • 2.25 gm

  56. Aminoacid present in high concentration in brain tissues
    • Glutamic acid
    • Lysine
    • Arginine
    • Proline

  57. Locally applied protein precipitants with low cell permeability are known as
    • Epilatories
    • Astringents
    • Humactants
    • Keratolytics

  58. Metal cylinders filled with nitrous oxide for hospital use is painted in
    • Blue
    • Grey
    • White
    • Black

  59. Which of the following is not a legal requirement for opening a drug store?
    • Location
    • Minimum space
    • Drug licence
    • Store arrangements

  60. Lanolin is also known as
    • Carnauba wax
    • Anhydrous wool fat
    • Hydrous wool fat
    • Spermaceti

  61. Common adverse effect of thrombolytics
    • Bleeding
    • Unstable angina
    • Arterial occlusion
    • Myocardial infarction

  62. Citral is the major constituent of
    • Turpentine oil
    • Lemon grass oil
    • Peppermint oil
    • Cardomom oil

  63. The dosage form in which fluid containing the drug is retained in the rectum for the drug to act either locally or systemically
    • Retention enema
    • Suppositories
    • Evacuant enema
    • Lotion

  64. Semisolid dosage forms with high percentage of insoluble solid medicaments
    • Creams
    • Pastes
    • Gels
    • Jellies

  65. Coriander leaves are rich source of
    • Vitamin A
    • Volatile oil
    • Geraniol
    • Pinene

  66. Convenient dosage form to deliver pellets or granular material orally
    • Hard gelatin capsule
    • Soft gelatin capsule
    • Layered tablets
    • Compressed tablets

  67. In economic order quantity, which of the following should be minimum?
    • Ordering cost and carrying cost
    • Ordering cost
    • Carrying cost
    • Ordering quantity

  68. Which of the following is an oleo gum resin?
    • Myrrh
    • Storax
    • Colocynth
    • Colophony

  69. The breakdown of a tablet into smaller particles or granules is known as
    • Disintegration
    • Crushing
    • Dissolution
    • Granulation

  70. The extent to which a patient's medication taking behavior coincides with the intention of health advice is known as
    • Monitoring
    • Adherence
    • Drug utilization
    • Purchasing power

  71. Glycoside present in Nux vomica
    • Strichnine
    • Loganine
    • Ecgonine
    • Quinovine

  72. Which of the following uses the violent turbulence of the air and steam to reduce the particle size by inter particular attrition?
    • Cutting mill
    • Fluid energy mill
    • Roller mill
    • Colloid mill

  73. Which among the following is a phase II reaction of drug metabolism?
    • Oxidation
    • Conjugation
    • Reduction
    • Hydrolysis

  74. The equipment used for moist heat sterilization
    • Hot air oven
    • Cartridge filter
    • Autoclave
    • Cyclone separator

  75. Which of the following technique is used to increase the solubility of weak electrolytes and non-polar molecules by the addition of a water miscible solvent in which the drug has good solubility?
    • Complexation
    • Solubilization
    • Hydrotrophy
    • Co solvency

  76. The most important influence of temperature on emulsion stability
    • Creaming
    • Caking
    • Cracking
    • Phase inversion

  77. Green vitriol is known as
    • Copper sulphate
    • Ferric ammonium citrate
    • Ferrous sulphate
    • Ferrous gluconate

  78. The approved indication of Lurasidone
    • Depression
    • Mania
    • Parkinsonism
    • Schizophrenia

  79. One fluid ounze volume is equal to
    • 45 ml
    • 60 ml
    • 15 ml
    • 30 ml

  80. Boiling water is poured over the drug and allowing to keep in contact with the drug for 15 minutes with occasional stirring and finally filtered off without pressing the marc. This process is known as
    • Maceration
    • Infusion
    • Percolation
    • Decoction

  81. Largest inhabited Riverine Island in the World
    • Gowalkot
    • Kabirvad
    • Majuli
    • Bhavani

  82. Koyna River Valley Project is in
    • Madhya Pradesh
    • Maharashtra
    • Sikkim
    • Himachal Pradesh

  83. Ghadprabha Bird Sanctuary is situated in
    • Belgaum
    • Bharatpur
    • Shivpuri
    • Coorg

  84. The shape of the Deccan Plateau
    • Triangular
    • Rectangular
    • Square
    • Hexagonal

  85. The hero in the Sanskrit drama Mudra Rakshasa of Visaghadatta.
    • Chanakya
    • Ashoka
    • Chandra Gupta Maurya
    • Samudra Gupta

  86. The adopted son of Peshwa Baji Rao II was fought in the Revolt of 1857
    • Kunwar Singh
    • Mangal Panday
    • Nana Sahib
    • Thantia Topi

  87. Ram Muhammed Singh Azad is famous in Indian freedom struggle as
    • Chandra Sekhar Azad
    • Khudiram Bose
    • Udam Singh
    • Muhammed Iqbal

  88. Thannirmukkam Bundu is situated in
    • Sasthamkotta lake
    • Ashtamudi lake
    • Punnamada lake
    • Vembanadu lake

  89. A river flowing through the Silent Valley area
    • Chalakkudi Puzha
    • Prambikulam River
    • Muthira Puzha
    • Kunthi Puzha

  90. The only plateau in Kerala
    • Waynadu
    • Palghat
    • Nilgiris
    • Idukki

  91. The first Vice Chancellor of the University of Travancore.
    • Sree Chittira Thirunal Bala Rama Varma
    • Sir C. P. RamaSwamy Iyyer
    • P.G.N. Unnithan
    • Dr. John Mathai

  92. The person who established the Advaita Ashram at Aluva
    • Chattampi Swamikal
    • Swami Vivekananda
    • Sankaracharya
    • Sree Narayana Guru

  93. Name the social reformer who became member of Sree Moolam Praja Sabha.
    • Vagbhatananda
    • Ayya Vaikundar
    • Pandit Karuppan
    • Ayyankali

  94. Dr. Palpu is in connection with
    • Ezhava Memorial
    • Civic Rights Agitation
    • Malayali Memorial
    • Nivarthana Agitation

  95. Tomb of Kuriakose Elias Chavara is situated at
    • Manganam
    • Mannanam
    • Munnar
    • Mannar

  96. Nicolas Maduro became the President of
    • Argentina
    • Brazil
    • Cuba
    • Venezuela

  97. The founder director of CSIR-Centre for Cellular Molecular Biology
    • Bala Subrahmanian
    • Sarat Chandra
    • P. M. Bhargava
    • Abdul Kalam

  98. Which country won the ICC Women's World Cup Final 2017?
    • Australia
    • England
    • India
    • West Indies

  99. Dad Saheb Phalke Award 2016 was received by
    • Manoj Kumar
    • Sasi Kapoor
    • K.Viswanathan
    • Gulzar

  100. Recipient of the Ezhuthachan Award 2016.
    • Vishnu Narayanan Namboothiri
    • C. Radha Krishnan
    • Puthusseerry RamaChandran
    • M. K. Sanu

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