Assistant Professor in physiology 151/2018, 152/2018 Answer Key

physio

Post: Assistant Professor in physiology
Department: Medical Education
Category Code: 151/18, 152/18
Qualification: MD (Physiology)/ DNB (Physiology) + Three year teaching experiance
Date of Test: 11-06-2019


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  1. Which of the following proteins are called as folding proteins?
    • Perforins
    • Chaperons
    • Tubulins
    • Clathrins

  2. Enzyme which converts testosterone to estradiol in ovarian follicle is
    • Isomerase
    • Dehydrogenase
    • Aromatase
    • Transferase

  3. Fusion of sperm with membrane of ovum is mediated by
    • Acrosin
    • Fertilin
    • Catsper
    • Inhibin

  4. The main excitatory neurotransmitter in central nervous system is
    • Glutamate
    • Substance P
    • Enkephalin
    • Serotonin

  5. Bicarbonate reabsorption is maximum in
    • Medullary collecting duct
    • Distal convoluted tubule
    • Proximal convoluted tubule
    • Cortical collecting duct

  6. Fibres from ipsilateral hemiretina project in which layer of lateral geniculate body
    • 1,4,6
    • 2,3,5
    • 1,3,6
    • 2,4,6

  7. All of the following are dopamine agonists EXCEPT
    • Bromocriptine
    • Apomorphine
    • Clozapine
    • Pramiprexole

  8. The inclusion bodies seen in neurons of parkinsonism patients are
    • Lewy bodies
    • Russell bodies
    • Negri bodies
    • Schaumann bodies

  9. The substance that is present both in serum and plasma is
    • Prothrombin
    • Antihaemophilic factor A
    • Fibrinogen
    • Proconvertin

  10. An agent which causes contraction of mesangial cells is
    • Atrial natriuretic peptide
    • Dopamine
    • cAMP
    • Endothelins

  11. Cerebellar nystagmus occurs due to damage to
    • Anterior lobe
    • Flocculonodular lobe
    • Posterior lobe
    • Vermis

  12. Type of cell NOT present in olfactory bulb
    • Mitral cell
    • Granule cell
    • Tufted cell
    • Horizontal cell

  13. Which of the following is increased when radius of resistance vessels is increased?
    • Haematocrit
    • Diastolic blood pressure
    • Capillary blood flow
    • Systolic blood pressure

  14. Which of the following is NOT a cause of edema?
    • Decreased capillary permeability
    • Decreased plasma protein
    • Increased venous pressure
    • Inadequate lymph flow

  15. Dicrotic notch in aortic pressure curve is caused by closure of
    • Tricuspid valve
    • Pulmonary valve
    • Mitral valve
    • Aortic valve

  16. Fourth heart sounds is caused by
    • Closure of aortic and pulmonary valve
    • Ventricular filling
    • Closure of mitral and tricuspid valve
    • Vibrations in ventricular wall during systole

  17. Largest volume of gas that can be moved into and out of the lungs in one minute by voluntary effort is
    • Respiratory minute volume
    • Forced vital capacity
    • Maximum voluntary ventilation
    • Total lung capacity

  18. Which of the following plays a major role in vasodilatation of penis during erection?
    • Nitric oxide
    • Vasopressin
    • Bradykinin
    • Prostaglandin

  19. Sensory system codes for the following attributes of a stimulus EXCEPT
    • Modality
    • Sensitization
    • Intensity
    • Location

  20. Which of the following is NOT a characteristic of smooth muscle?
    • Slow cycling of myosin cross bridges
    • Low energy requirement to sustain contraction
    • Stress relaxation
    • Maximum force of contraction is less than that of skeletal muscle

  21. Duration of AV nodal delay is
    • 0.1 seconds
    • 0.3 seconds
    • 0.5 seconds
    • 0.7 seconds

  22. Second polar body is extruded
    • At the time of ovulation
    • At the time of LH surge
    • At the time of fertilization of the ovum
    • 48 hours prior to ovulation

  23. Compound action potential is the property of
    • Sensory nerve
    • Mixed nerve
    • Single nerve fibre
    • Motor nerve

  24. The wheal in triple response occurs due to
    • increased capillary permeability
    • arteriolar dilation
    • axon reflex
    • contraction of precapillary sphincters

  25. Which of the following has the highest pH?
    • Saliva
    • Gastric juice
    • Gall bladder bile
    • Pancreatic juice

  26. EEG rhythm with lowest frequency is
    • Alpha
    • Beta
    • Delta
    • Theta

  27. Effective renal plasma flow in humans is
    • 425 ml/min
    • 525 ml/min
    • 625 ml/min
    • 725 ml/min

  28. Group A nerve fibres are most susceptible to
    • Pressure
    • Hypoxia
    • Temperature
    • Local anaesthetics

  29. Which of the following is a peptide hormone?
    • Estrogen
    • Parathormone
    • Thyroxine
    • Cortisol

  30. Sperms persist in female genital tract for
    • 1-2 minutes
    • 1-2 hours
    • 1-2 days
    • 1-2 weeks

  31. Water reabsorption is maximum from
    • duodenum
    • colon
    • ileum
    • jejunum

  32. The most abundant cell type in Islets of Langerhans is
    • A
    • B
    • D
    • F

  33. Work done in quiet breathing is
    • 0.1 kg-m/min
    • 1.2 kg-m/min
    • 0.5 kg-m/min
    • 3.5 kg-m/min

  34. Conversion of fibrinogen to fibrin is catalysed by
    • Thromboplastin
    • Stuart Prower Factor
    • Proconvertin
    • Thrombin

  35. Which of the following causes a right shift of oxygen dissociation curve?
    • Decrease in body temperature
    • Foetal haemoglobin
    • Myoglobin
    • Decrease in blood pH

  36. Which of the following is NOT an example of syndromic deafness?
    • Liddle's syndrome
    • Pendred syndrome
    • Long QT syndrome
    • Bartter syndrome

  37. Which sensation is not lost on the same side of lesion in Brown Sequard Syndrome?
    • Position sense
    • Vibration
    • Temperature
    • Touch

  38. Heavy water is used to determine
    • Intracellular fluid volume
    • Extracellular fluid volume
    • Plasma volume
    • Total body water

  39. Spermatozoa acquire motility in
    • Vas deferens
    • Epidydimis
    • Rete testis
    • Prostate

  40. Functional residual capacity in male is
    • 2.2 L
    • 3.2 L
    • 4.2 L
    • 5.2 L

  41. Glial cells which help in making Blood brain barrier are
    • Oligo dendrocytes
    • Schwann cells
    • Astrocytes
    • Microglia

  42. Weber Fechner law deals with
    • Receptive field organization
    • Intensity discrimination
    • Tactile localization
    • None

  43. Which of the following is an Orexigenic factor?
    • Corticotropin releasing hormone
    • Glucagon
    • Leptin
    • Neuropeptide Y

  44. Stokes Adams syndrome is loss of consciousness following
    • Ventricular fibrillation
    • Complete heart block
    • Myocardial infarction
    • Ventricular tachycardia

  45. Effect of storage of blood on RBCs are all EXCEPT
    • RBCs become spherical
    • Depletion of ATP
    • Loss of membrane stability
    • Increased glycolysis

  46. Prosapagnosia is the inability to
    • Draw straight lines
    • Recognize faces
    • Count in order
    • Perceive pain

  47. Which of the following is facilitatory to stretch reflex?
    • Vestibular nucleus
    • Cerebellum
    • Motor cortex
    • Basal ganglia

  48. Betz cells are found in
    • Thalamus
    • Hypothalamus
    • Motor cortex
    • Sensory cortex

  49. Gastric acid secretion is stimulated by all EXCEPT
    • Acetyl choline
    • Histamine
    • Secretin
    • Gastrin

  50. Lesion in angular gyrus produces
    • Motor aphasia
    • Sensory aphasia
    • Conductive aphasia
    • Anomic aphasia

  51. The blobs of visual cortex are associated with
    • Colour processing
    • Orientation
    • Ocular movements
    • Ocular dominance

  52. Which of the following is an example of a trinucleotide repeat disease?
    • Wilson's disease
    • Cystic fibrosis
    • Hereditary spherocytosis
    • Huntington's disease

  53. Muscle weakness caused by antibodies against calcium channels in nerve endings at neuromuscular junction is seen in
    • Myaesthenia gravis
    • Lambert Eaton syndrome
    • Multiple sclerosis
    • Muscular dystrophy

  54. K cells of intestine secrete
    • Secretin
    • Vasoactive Intenstinal Pepide
    • Gastric Inhibitory Peptide
    • Cholecystokinin

  55. All are produced by kidney EXCEPT
    • Vitamin D
    • Renin
    • Erythropoietin
    • Aldosterone

  56. The principal buffer in interstitial fluid is
    • Carbonic acid
    • Phosphate
    • Haemoglobin
    • Ammonia

  57. Blood flow is almost always turbulent when Reynold's number is more than
    • 2000
    • 3000
    • 4000
    • 5000

  58. Respiratory burst in neutrophil is due to
    • NADH oxidase
    • Elastase
    • Myeloperoxidase
    • NADPH oxidase

  59. Cholagogues are substances which cause
    • Increases biliary secretion from liver
    • Neutralizes acid chyme
    • Contraction of gall bladder
    • Helps in absorption of fat soluble vitamins

  60. Bicarbonate in gastric mucosal barrier is secreted from
    • Chief cells
    • Oxyntic cells
    • Surface mucosal cells
    • Neck cells

  61. Mechanism by which digitalis increases myocardial contractility is by
    • Inhibiting sodium potassium pump
    • Activating protein kinase
    • Decreasing adrenaline levels in myocardium
    • Decreasing break down of Camp

  62. Migrating motor complex is initiated by
    • Guanylin
    • Motilin
    • Peptide YY
    • Somatostain

  63. Fluctuations in blood pressure synchronized with respiration are
    • Traube Hering Waves
    • Mayer waves
    • Slow waves
    • Gamma oscillations

  64. Example of a condition which cause distributive shock is
    • Hemorrhage
    • Burns
    • Anaphylaxis
    • Tension pneumothorax

  65. Hyperbaric oxygen therapy is of no use in
    • Carbon monoxide poisoning
    • Gas gansrene
    • Diabetic leg ulcer
    • Congestive cardiac failure

  66. During exercise, arterio venous oxygen difference
    • Increases
    • First decreases then increases
    • Decreases
    • Remains same

  67. The first urge to pass urine is felt as urinary bladder volume of
    • 100 ml
    • 150 ml
    • 250 ml
    • 300 ml

  68. All of the following are effects of prolonged stay in space EXCEPT
    • Decrease in red cell mass
    • Loss of bone mass
    • Increase in blood volume
    • Decrease in muscle strength

  69. Which of the following diuretic acts on proximal tubule?
    • Spironolactone
    • Amiloride
    • Frusemide
    • Acetazolamide

  70. Which of the following increases extracellular potassium concentration?
    • Insulin
    • Aldosterone
    • Alkalosis
    • Severe exercise

  71. Which of the following is NOT a component of Papez circuit?
    • Cingulate gyrus
    • Mammilary body
    • Posterior thalamic nucleus
    • Hippocampus

  72. A mutation in KALIG1 gene is seen in
    • Kartagener's syndrome
    • Kallmann syndrome
    • Klinfelter's syndrome
    • Kluver Bucy syndrome

  73. The protein which connects Z line to M line and provides scaffolding for sarcomere is
    • Titin
    • Desmin
    • Actinin
    • Troponin

  74. The average arm to tongue circulation time is
    • 5 seconds
    • 10 seconds
    • 15 seconds
    • 20 second

  75. Human Chorionic Gonadotropin acts on
    • LH receptor
    • FSH receptor
    • TSH receptor
    • ACTH receptor

  76. Effect of deafferentation of bladder is
    • Shrunken and hypertrophied wall
    • Spastic with hyperactive voiding reflex
    • Overfilled with dribbling
    • Distended, thin walled and hypotonic

  77. The diluting segment of nephron is
    • Proximal convoluted tubule
    • Thick ascending limb of loop of Henle
    • Descending limb of loop of Henle
    • Medullary collecting duct

  78. Oral contraceptive pills act by
    • Inhibiting ovulation
    • Decreasing motility of sperms
    • Spermicidal action
    • Increasing motility of fallopian tubes

  79. The Poiseuille Hagen formula calculates relation among the following EXCEPT
    • Flow in a narrow tube
    • pH of blood
    • Raidus of the tube
    • Viscosity of blood

  80. Gap junctions are made up of proteins called
    • Connexons
    • Caspases
    • Dyneins
    • Cadherins

  81. Which state has become India's first state to bring a law against 'sextortion'?
    • Himachal Pradesh
    • Jammu and Kashmir
    • Manipur
    • Kerala

  82. The national milk day (NMD-2018) is celebrated on which of the following dates in India?
    • November 26
    • December 16
    • January 24
    • February 2

  83. India's longest rail-cum road bridge is located in which of the following states?
    • Arunachal Pradesh
    • Nagaland
    • Assam
    • Meghalaya

  84. Auther of "Ananda Sutram"
    • Sreenarayana Guru
    • V T Bhatathirippad
    • Poikayil Yohannan
    • Brahmananda Sivayogi

  85. Who is known as Muthukutti Swami?
    • Vaikunda Swamikal
    • Chattambi Swamikal
    • Swami Vagbhatananda
    • Swami Agamananda

  86. The newspaper Sujana nadhini started from Paravur in
    • 1896
    • 1891
    • 1887
    • 1889

  87. Ruler of Travancore during the time of Vaikkam Sathyagraha
    • Gouri Parvathi Bai
    • Sri Mulam Tirunal
    • Ayilyam Tirunal
    • Regent Setu Lakshmi Bai

  88. Who was the captain of Guruvayur Temple entry campaign?
    • T. Subramanian Tirumumbu
    • K. Kelappan
    • P. Krishna Pillai
    • Mannathu Padmanabhan

  89. Who entered on an indefinite fast before Guruvayur temple on Sep 21, 1932 in connection with Guruvayur Sathayagraha?
    • A.K. Gopalan
    • Mannathu Padmanabhan
    • K. Kelappan
    • P. Krishna Pillai

  90. Yoga Kshema movement started in
    • 1908
    • 1904
    • 1901
    • 1907

  91. Where did Sree Narayana Guru installed the idol of Saraswathi?
    • Aruvipuram
    • Varkala
    • Alwaye
    • Karamukku

  92. Who opened an English school at Mattancheri in 1818?
    • Rev Mead
    • Dr. Gundert
    • W.T. Ringletaube
    • Rev. J. Dawson

  93. Who abolished the devadasi system in temples of south Travancore?
    • Sethu Lakshmi Bai
    • Gouri Parvathi Bai
    • Sri Chitra Tirunal
    • Uthradam Thirunal

  94. Tellicherry Brennen School started in
    • 1862
    • 1852
    • 1886
    • 1902

  95. Ayyankali was called pulayaraja by
    • B.R. Ambedkar
    • M.K. Gandhi
    • Sreenarayana Guru
    • G.P. Pillai

  96. Auther of the novel "Premamrutham"
    • C.V. Raman Pillai
    • P. Kesavdev
    • Thakazhi Sivasankara Pillai
    • S.K. Pottekkad

  97. Who was the provisional president of constituent assembly in India?
    • Dr. B.R. Ambedkar
    • Dr. Rajendra Prasad
    • Sardar Vallabhai Pattel
    • Dr. Sachidananda Sinha

  98. In which year was the right to property removed from fundamental rights of Indian Constitution?
    • 1978
    • 1973
    • 1969
    • 1979

  99. Which among the following amendment of Indian Constitution replaced the right to property from fundamental rights?
    • 44th amendment
    • 43rd amendment
    • 42nd amendment
    • 46th amendment

  100. Fundamental duties of citizens were added to the Indian Constitution in
    • 1974
    • 1976
    • 1978
    • 1972

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