Post : Assistant Professor in Nuclear Medicine
Department : Medical Education Service
Category Code : 421/16
Qualification : Medical Post Graduate Degree + Three years Teaching Experience
Question Paper Code : 19/18
Date of Test : 05-02-2018
- Regulatory authority for the use of radiopharmaceuticals in India :
- FDA
- AERB
- RPC
- All these
- If 99mTc-MDP contains 99mTc-pertechnetate as an impurity it will be accumulated in :
- Bone
- Liver
- Thyroid
- All of these
- Radiochemical impurity expected in 99mTc eluates is :
- Reduced hydrolysed technetium
- Molybdenum - 98 species
- Molybdenum - 99 species
- Sodium Pertechnetate
- B.E.T Stands for :
- Bacterial Endotoxin Test
- Bacterial Environment Test
- Biosafety Exhaust Test
- Bacterial Exotoxin Test
- In a Symbol 131I, the number 131 stands for :
- number of neutrons
- number of protons
- number of electrons
- number of nucleons
- The presence of chemical impurities in 99mTc-compounds will lead to :
- undue toxicity
- Poor labelling
- both undue toxicity and Poor labelling
- None of these
- 99mTc-MIBI accumulates in myocardium by :
- Active transport
- Passive diffusion
- Chemisorption
- Compartment localisation
- Cadmium rod is used in Nuclear Reactor as :
- Moderator
- Cladding material
- Fuel
- Control rod
- In a period of six half lives, the activity of a material reduces to :
- 1/16 of its initial activity
- 1/8 of its initial activity
- 1/32 of its initial activity
- 1/64 of its initial activity
- Enumeration of microbial contamination in environment is indicated by :
- Colour development
- Spore development
- Colony development
- None of these
- 99Mo-99Tc generator system belongs to :
- transient equilibrium
- no equilibrium
- secular equilibrium
- None of these
- The most popular Bone imaging agent is :
- 99mTc-MDP
- 18F-NaF
- Tc-99m HEDP
- F-18 FDG
- Distinct property of 201Thallium Chloride in Myocardial perfusion imaging compared to Technetium-99m agents.
- infarct uptake
- myocardial uptake
- redistribution
- tumour uptake
- 99mTc(V)-DMSA is useful for imaging :
- Colorectal cancer
- Medullary thyroid cancer
- Differentiated thyroid cancer
- Ovarian cancer
- 99mTc-ECD is preferable to 99mTc-HMPAO because of :
- ease of preparation
- higher brain uptake
- stereospecificity
- in vitro stability
- Radioimmunoscintigraphy is based on :
- Immunotargetting
- Receptor binding
- Avidin-biotin system
- None of these
- Iodine-123 is commercially obtained from :
- Cyclotron
- Generator
- Reactor
- All of these
- The best radiographic technique for early esophageal carcinoma is :
- Computed tomography
- Endoscopic ultrasound
- Positron Emission Tomography
- Double contrast barium study
Question error
- 201Thallous Chloride enters the myocardium by :
- Reverse Osmosis
- Na+– K+ ATPase pump
- Passive Diffusion
- None of these
- Biological Quality control testing includes :
- Pyrogen test
- Sterility test
- Biodistribution studies
- All of these
- In Radioimmunoassay, the relation between intensity of radioactivity and concentration of antigen in the test sample is :
- Inverse
- Direct
- Exponential
- No relation
- Generator produced PET Tracer :
- Rubidium - 81
- Technetium - 99m
- Gallium - 68
- Indium - 113m
- Dose limiting organ in most radionuclide therapies.
- Kidney
- Bone marrow
- Colon
- Liver
- PET Agent used for myocardial perfusion imaging :
- 13N-Ammonia
- 18F-FDG
- 99mTc-MIBI
- 201Thallium Chloride
- Critical Organ in 99mTc-MIBI myocardial perfusion imaging :
- Heart
- Proximal colon
- Liver
- Stomach
- Half life of Iodine-131 :
- 3 days
- 13.6 hours
- 8 days
- 60 days
- Radioisotope used for painful bone metastasis :
- Samarium 153
- Iodine 131
- Technetium 99m
- Gallium 67
- 99MTc-sodium pertechnetate can be used for all the following except :
- Thyroid imaging
- Salivary gland imaging
- Infection imaging
- Meckels diverticulum detection
- When performing Iodine-123 imaging, breastfeeding can be safely resumed after?
- 2 - 3 days
- 12 to 24 hours
- 4 hours
- cannot be resumed
- Energy of Gamma rays emitted in Positron Emission Tomography :
- 140 keV
- 511 keV
- 364 keV
- 185 keV
- Incidence of thyroid cancer is higher in which thyroid scintigraphy pattern?
- Hot nodule
- Absence of thyroid uptake
- Homogenous increased uptake
- Cold nodule
- Most common false positive finding in parathyroid scanning :
- Thyroid adenoma
- Parathyroid adenoma
- Parathyroid hyperplasia
- Activity in oropharynx
- In Bone Scan of a patient with known malignancy, chance of a solitary Rib lesion being malignant is :
- 40-50%
- 70-80%
- 10-20%
- 2-5%
- Causes of positive Three phase bone scan can be all the following except :
- Recent fracture
- Soft tissue infection
- Charcots joint
- Osteomyelitis
- In cholescintigraphy for evaluation of neonatal jaundice, absence of biliary clearance is consistent with :
- Neonatal hepatitis
- Acute cholecystitis
- Chronic cholecystitis
- Biliary Atresia
- Radiopharmaceutical commonly used for measuring GFR :
- Tc-99m MAG3
- I-131 Ortho Iodo Hippurate (OIH)
- Tc-99m DTPA
- Tc-99m DMSA
- Webster’s rule applies to :
- Dose calculation in renal insufficiency
- Myocardial imaging
- Cerebral perfusion imaging
- Dose calculation in paediatrics
- Captopril renography is done in the workup of :
- Renal artery stenosis
- Renal vein thrombosis
- Pyelonephritis
- None of these
- The accuracy of diuretic renography is affected by :
- Renal function
- Dose of diuretic
- Bladder capacity
- All of these
- The sensitivity of FDG PET is high in :
- Primary hepatocellular carcinoma
- Prostate carcinoma
- Colorectal cancer
- Renal carcinoma
- Sentinel node scintigraphy in melanoma is indicated in primary lesion of size :
- < 1 mm
- 1 to 4 mm
- > 4 mm
- Both "< 1 mm" and "1 to 4 mm"
- Preferred method for radiolabelling of RBCs :
- In vivo method
- Modified In vivo method
- In vitro method
- Any of these
- Multiple photopeak energies are acquired for imaging of :
- Gallium-67
- Technetium-99m
- Gallium-68
- Iodine-131
- Pulmonary Gallium - 67 uptake is not seen in :
- Sarcoidosis
- Histoplasmosis
- Kaposis sarcoma
- Cytomegalovirus infection
- Which of the following finding suggests triple vessel disease in a myocardial perfusion imaging?
- reduced anterior wall uptake
- exercise induced ischemic dilatation
- lung uptake on delayed images
- reduced anterior and lateral wall uptake
- Reversible stress induced hypoperfusion of the septum is seen in :
- Triple vessel disease
- Stress induced ischemia
- WPW syndrome
- Left Bundle branch block
- According to the 2007 ICRP recommendations, tissue weighting factor for Gonads is :
- 0.12
- 0.04
- 0.08
- 0.01
- Recommended Effective dose limit for occupational exposure in a year (average) is :
- 500 mSv
- 150 mSv
- 15 mSv
- 20 mSv
- A gamma camera crystal consists of :
- Sodium Iodide activated with Thallium
- Cesium Iodide doped with Thallium
- Germanium doped with Lithium
- Cadmium Zinc Telluride
- Most common type of collimator used in gamma cameras :
- Pin Hole Collimator
- Parallel Hole Collimator
- Diverging Collimator
- Converging Collimator
- In performing Quality control of a Gamma Camera, Spatial Resolution should be done :
- daily
- at installation
- weekly
- monthly
- On a bone scan, pin hole collimation can be used in :
- Legg-Calve-Perthes Disease
- Multiple Myeloma
- Rib Fracture
- None of these
- Which Radiopharmaceutical among bone imaging agents is superior in localizing necrotic tissue?
- Tc-99m MDP
- Tc-99m HDP
- Tc-99m HEDP
- Tc-99m pyrophosphate
- Maximum predicted heart rate is calculated by :
- 180-age
- 240-age
- 220-age
- age in years×4
- Left anterior descending coronary artery supplies :
- Anterior and lateral walls
- Lateral and Posterior walls
- Anterior wall and the septum
- Inferior wall and right ventricle
- Poor in vivo RBC labelling can be caused by :
- drug interactions
- incorrect amount of stannous ion
- inappropriate procedure
- all these
- Reduced ventricular contraction while assessing wall motion on a radionuclide ventriculogram is denoted as :
- dyskinesis
- hypokinesis
- akinesis
- tardokinesis
- Tracers used in blood brain barrier imaging are all except :
- Tc-99m pertechnetate
- Tc-99m DTPA
- Tc-99m ECD
- Tc-99m Glucoheptonate
- Best tracer to diagnose venous sinus thrombosis :
- Tc-99m HMPAO
- Tc-99m ECD
- Tc-99m Glucoheptonate
- Tc-99m RBCs
- Paradoxical blocking of iodine incorporation into thyroid hormones from excess iodine :
- Jod-Basedow phenomenon
- Wolff - Chaikoff effect
- Riedel’s thyroiditis
- Marine - Lenhart syndrome
- Which of the following radiopharmaceuticals can be used in thyroid imaging?
- Tc-99m DMSA
- F-18 FDG
- Tc-99m MDP
- Tc-99m HMPAO
Question error
- Symmetric decrease in perfusion and metabolism in Alzheimers disease is seen in :
- Posterior parietal lobe
- Occipital lobe
- Temporal parietal lobe
- Frontal lobe
- Specificity for detection of pheochromocytoma using I-131 MIBG imaging is around :
- 95%
- 60%
- 90%
- 80%
- Sensitivity of a bone scan is highest for :
- Prostate
- Breast
- Lung
- Renal cell carcinoma
- Though I-123 is the ideal thyroid imaging agent, it is not commonly used because of all the following except :
- short half life
- can be stored for future use
- expensive
- not readily available
- Lugols iodine or potassium perchlorate to block thyroid uptake while administering I-131 MIBG should be continued for :
- 24 hours
- 48 hours
- 7 days
- 14 days
- High probability of pulmonary emboli in the modified PIOPED Criteria :
- multiple perfusion defects with associated radiographic opacities
- triple match: solitary moderate-large matching segmental defect with matching radiograph
- matched ventilation and perfusion defects with a normal chest radiograph
- any perfusion defect substantially larger than the radiographic abnormality
- Sequence of performing ventilation and perfusion studies while using Xe-133 and Tc-99m respectively should be :
- Perfusion study followed by ventilation study
- Ventilation study followed by perfusion study
- Both studies simultaneously
- Either studies can be performed in any sequence
- Drug which is not used for pharmacological stress testing?
- Dipyridamole
- Adenosine
- Regadenoson
- Metoprolol
- Nuclear Sialography is performed using :
- Tc-99m pertechnetate
- Tc-99m sulfur colloid
- Ga-67 Citrate
- Tc-99m labelled RBCs
- The most important parameter which determines the actual amount of exposure the patient receives during a nuclear medicine procedure :
- Biological half life
- Physical half life
- Effective half life
- Both Biological half life and Effective half life
- Dose of recombinant human TSH injection used in Thyroid cancer imaging using Iodine - 131.
- 0.3 mg for two consecutive days
- 0.9 mg for two consecutive days
- 0.45 mg for two consecutive days
- 0.6 mg for two consecutive days
- The type of emissions used in radionuclide therapy are all except :
- Beta rays
- Gamma rays
- Auger electrons
- Alpha particles
- An interaction in which a gamma photon loses all of its energy to an inner shell electron is :
- Annihilation reaction
- Pair production
- Compton effect
- Photoelectric effect
- PET Tracer used in hypoxia imaging :
- Gallium-68 Dotatate
- F-18 misonidazole
- F-18 FDG
- F-18 DOPA
- Radionuclide used in palliative bone metastases treatment which can also be imaged :
- Strontium-89
- Phosphorus-32
- Rhenium-186
- None of these
- False negative lung findings on a PET-CT is seen in :
- Tuberculosis
- Squamous cell carcinoma
- Sarcoidosis
- Bronchioalveolar carcinoma
- In Prostate Carcinoma imaging which of the following is false?
- Most primary prostate carcinomas demonstrate high uptake of F-18 FDG
- FDG PET is not reliable in differentiating carcinoma from benign prostate hypertrophy
- FDG PET has less sensitivity in assessing lymph node metastases
- Bone scan is more sensitive than PET in detecting bone metastases
- Low to moderate FDG uptake is seen in :
- Hodgkins lymphoma
- Peripheral T cell lymphoma
- Diffuse large B-cell lymphoma
- Mantle cell lymphoma
- High uptake in colon in an FDG PET can occur in :
- Adenoma
- Diverticulitis
- Carcinoma
- Any of these
- The largest inland saltwater lake in India, namely Sambhar Lake is located in __________.
- Orissa
- Bihar
- West Bengal
- Rajasthan
- Of the following rivers which is the tributary of Narmada?
- Musi
- Indravati
- Hiran
- Kapila
- Gomal and Bolan Passes run through the __________.
- Himalayas
- Western Ghats
- Aravalli Hills
- Vindhya-Satpura ranges
- Which historian made the following argument while analyzing the character of the Revolt of 1857?
“The revolt of 1857 cannot be regarded as national in the full modern sense of the word. Though the sentiment was anti-foreign, there was no positive national content in it.”- Susobhan Sarkar
- A.R. Desai
- S.B. Chaudhuri
- P.C. Joshi
- The ‘Quit India’ resolution was passed by the Bombay session of the AICC on __________.
- 9th August 1942
- 8th August 1942
- 6th August 1942
- 7th August 1942
- Who formed a Samiti namely Swadesh Bandhab Samiti in Barisal to spread swadeshi messages among the masses after the partition of Bengal in 1905?
- Bipin Chandra Pal
- Mukunda Das
- Ashwin Kumar Dutt
- Lala Lajpat Rai
- Who among the following freedom fighter was NOT associated with the Ghadar movement?
- Lala Hardayal
- Ram Chandra
- Barkathullah
- B.K. Dutt
- Who played a leading role in drafting the Five Year Plan of 1956-61?
- Prof. P.C. Mahalanobis
- Prof. K.N. Raj
- V.K.R.V. Rao
- Raj Chandra Bose
- Porkalam, Cheramangad and Pazhayannur are the major __________ sites excavated in Kerala.
- Megaliths
- Mesolithic
- Neolithic
- Palaeolithic
- Which Pass in the Western Ghat connects Madurai district in Tamilnadu with the High Ranges in Idukki district?
- Aruvaimozhi Pass
- Perambadi Pass
- Bodinayakannur Pass
- Periya Pass
- Among the following works which one is written by Brahmananda Sivayogi?
- Pracheena Malayalam
- Mokshapradeepam
- Jathikkummy
- Vedadhikara Niroopanam
- Name the social reformer and poet of Kerala who received the titles namely Sahityanipunan and Kavitilakan from Valiya Tampuran of Cochin.
- Kumaranasan
- Vengayil Kunhiraman Nair
- Thycaud Ayya
- Pandit Karuppan
- The “Yachana Yatra” in 1931 from Thrissur to Kasargod on foot, was conducted under the leadership of which social reformer of Kerala.
- Kumara Guru
- Ayyankali
- V.T. Bhattathiripad
- Dr. Palpu
- P. Bhargavi Amma, M. Lakshmikutty Amma and K. Devayani were the important leaders of the women division of __________.
- Atma Vidya Sangham
- Yogakshema Sabha
- Prathyaksha Raksha Daiva Sabha
- Valamaha Sabha
- Match the following with the help of the CODES given below :
(a) Poikayil Yohannan
(b) Pandit Karuppan
(c) Vagbhatananda
(d) Ayya Vaikundar
Codes :
(i) Samatwa Samajam
(ii) Uralunkal AikyaNanaya Sangham
(iii) Prathyksha Raksha Daiva Sabha
(iv) Cochin Pulaya Maha Sabha- a-i, b-ii, c-iv, d-iii
- a-iii, b-iv, c-ii, d-i
- a-ii, b-i, c-iii, d-iv
- a-iv, b-iii, c-i, d-ii
- Name Japan’s men-only island recommended by UNESCO to its World Heritage list in May 2017.
- Okinawa
- Honshu
- Amami Oshima
- Okinoshima
- Who has been appointed as the Chairperson of the Centre Board of Film Certification (CBFC) by the Central Government from 11TH August 2017 for a period of three years?
- Pahlaj Nihalani
- Prasoon Joshi
- Anurag Srivastava
- Mukesh Bhatt
- Name the snake boat which won the 65th Nehru Trophy Boat Race on Punnamada Lake.
- Mahadevikad Chundan
- Payippadan Chundan
- Karichal Chundan
- Gabriel Chundan
- Who among the following Indian-origin girl secured two points higher than Albert Einstein and Stephen Hawking in the British Mensa IQ Test (162 Points).?
- Rajgauri Pawar
- Rajmukhi Pawar
- Mukta Pawar
- Neelam Pawar
- Which is the currency of Republic of Kiribati?
- U.S. Dollar
- New Zealand Dollar
- Australian Dollar
- Kina
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